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Effects of formaldehyde on morphometric structure of testis in Balb/C mice
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Mehdi Taghva   , Zahra Toutian 1, Simin Fazelipour |
| 1- , tootianz@vetmed.ut.ac.ir |
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Abstract: (15874 Views) |
Background: Formaldehyde is a suffocating gas with a sharp smell which enters the body from different ways and induces tissue damages. With respect to its effects damages on testis and the on testis and spermatozoa, the present study was conducted to determine the effects of formaldehyde on morphometric structure of testis in Balb/C mice.
Materials and methods: In an experimental research, a total of 40 adult mice of the bread Balb/C were selected and assigned in experimental and control groups. For this study 37% formaldehyde was injected intraperitoneally with four doses in a 40-day period. After weighting the mice, the abdomen was opened and the testes were weighted and subjected to morphometric study.
Results: Results showed that there were not significant differences between the experimental group and controls based on testes weight and morphometric structure, however, body weight and the ratio of the weight of two testes to body weight (GSI) did differ significantly.
Conclusion: It was showed that despite a significant reduction in body weight following the formaldehyde injection, the weight of testes and their dimensions were not changed. |
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| Keywords: Formaldehyde, Morphometric, Testis, Mouse. |
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Full-Text [PDF 106 kb]
(2696 Downloads)
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Subject:
Epidemiology
Received: 2006/09/6 | Published: 2007/06/15
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